BioNTech科學家夫妻、2022年德國最重要醫學獎項Paul Ehrlich Prize得主，研發出第一個COVID-19疫苗的內幕故事
2020年1月中新冠病毒肆虐全球前，生物技術公司BioNTech創始人Ugur Sahin告訴妻子、亦是他數十年的研究夥伴Özlem Türeci，在疫情結束前能開發出COVID-19疫苗，安全注射到數百萬人體內。
Ugur Sahin這股信心來自於近30年研究癌症腫瘤治療方式，發現的信使核糖核酸（messenger RNA，縮寫：mRNA）。他們認為這種不穩定且被忽略的分子，能重新引導免疫系統以對抗疾病。
本書由《金融時報》駐德國法蘭克福、專責BioNTech報導的記者Joe Miller主筆，Ugur Sahin及Özlem Türeci亦參與貢獻本書的寫作，同時收錄60多位科學家、政治家、公共衛生官員和BioNTech員工專訪，這本書還涵蓋疫情爆發後的關鍵事件，以及每項醫療創新的科學、經濟和個人背景各層面意義。
"我已經閱讀了Joe Miller這本巨作。Ugur Sahin早在1月24日已經意識到大流行的規模。我還沒那麼快。"---前任德國總理梅克爾（Angela Merkel）
"Ugur Sahin及Özlem Türeci已成為發現放射性元素鐳的瑪麗和皮耶居里之後，科學界最著名的夫妻檔"---英國《泰晤士報》（The Times）
"以引人入勝的方式爬梳Ugur Sahin及Özlem Türeci非凡成就，這對夫妻在信使核糖核酸的研發工作，得以快速開發Covid-19疫苗。" ---美國出版人周刊Publishers Weekly
Winners of the Paul Ehrlich Prize
The dramatic story of the married scientists who founded BioNTech and developed the first vaccine against COVID-19.
Nobody thought it was possible. In mid-January 2020, Ugur Sahin told Özlem Türeci, his wife and decades-long research partner, that a vaccine against what would soon be known as COVID-19 could be developed and safely injected into the arms of millions before the end of the year. His confidence was built upon almost thirty years of research. While working to revolutionize the way that cancerous tumors are treated, the couple had explored a volatile and overlooked molecule called messenger RNA; they believed it could be harnessed to redirect the immune system's forces against any number of diseases. As the founders of BioNTech, they faced widespread skepticism from the scientific community at first; but by the time Sars-Cov-2 was discovered in Wuhan, China, BioNTech was prepared to deploy cutting edge technology and create the world’s first clinically approved inoculation for the coronavirus.
The Vaccine draws back the curtain on one of the most important medical breakthroughs of our age; it will reveal how Doctors Sahin and Türeci were able to develop twenty vaccine candidates within weeks, convince Big Pharma to support their ambitious project, navigate political interference from the Trump administration and the European Union, and provide more than three billion doses of the Pfizer/BioNTech vaccine to countries around the world in record time.
Written by Joe Miller―the Financial Times’ Frankfurt correspondent who covered BioNTech’s COVID-19 project in real time―with contributions from Sahin and Türeci, as well as interviews with more than sixty scientists, politicians, public health officials, and BioNTech staff, the book covers key events throughout the extraordinary year, as well as exploring the scientific, economic, and personal background of each medical innovation. Crafted to be both completely accessible to the average reader and filled with details that will fascinate seasoned microbiologists, The Vaccine explains the science behind the breakthrough, at a time when public confidence in vaccine safety and efficacy is crucial to bringing an end to this pandemic.