The objective of this report is to invigorate and deepen the discussion about structural change in Africa and the appropriate trade and industrial policies that will allow countries in Africa to drive employment growth in higher value-added activities. This is based around (i) analytical work that clearly identifies the links from participation in RVCs and GVCs with structural change and development outcomes; (ii) an analysis of implications of current approaches to trade and industrial policies and how these could be reformed to allow African countries to better capitalize on the opportunities to drive structural change through participation in RVCs and GVCs. The analysis looks at national policies, the importance of regional cooperation, and coordination through regional economic communities and the implications for the Continental Free Trade Area in Africa and agreements with third countries, such as the EU and the US.