1. Dissolution and its correlation with the bioavailability of drugs:
For oral solid dosage forms dissolution test is the only in vitro quality control test
available to date which can provide insight to predict in vivo behavior, bioavailability,
the rate at which and the extent to which a drug reaches systemic circulation or the site of
action from an administered dosage form, of the drug product. The dissolution test serves as
a tool to distinguish between ’acceptable and unacceptable, bioequivalent, or bio
inequivalent, drug products.